Burnley (19) v Everton (8)
Resume: 12.30 pm. Venue: Turf Moore. On TV: Live on BT Sport 1.
Goalkeeper Nick Pope is in contention to return after missing out on a Manchester City defeat due to concussion. The midfield trio are available with Josh Brownhill, Robbie Brady and Dale Stephens.
Everton have no first-choice fullbacks – Lucas Digne (ankle), Seamus Coleman (hamstring) – so Bose Carlo Ancelotti is likely to remain in the 3-4-3 formation, with midfielders Tom Davis and Alex Iwobi in the back positions.
Last season: Everton 1 Burnley 0, Burnley 1 Everton 0
Last five league games: Burnley LLDWL; Everton LLLWL
Top scorers (all matches): Matej Vaidra & Chris Wood (Burnley) 2; Dominic Calvert-Levine (Everton) 13
Inconsistencies: H 3-1 A 19-20 D 5-2
Referee: Anthony Taylor (Cheshire)
Man City (11) v Fulham (17)
Resume: 3 p.m. Venue: Etihad Stadium. On TV: Live on BT Sport 1 and Premier Sports 1.
With the exception of record goal-scorer Sergio Aguero, City have a full-fit squad available, and although he returns to training after the knee, there is no risk against the Cotters.
Fulham manager Scott Parker has no new injuries and could make changes, but defender Kenny Tetek, who returned to training this week, will return to the game soon.
Last season: No related matches
Last five league matches: Man City DWDLW; Fulham LWLLW
Top scorers (all matches): Raheem Sterling & Ferran Torres (Man City) 5; Bobby Reid (Fulham) 4
Inconsistencies: H1-9a 22-1b 8-1
Referee: Jonathan Moss (County Durham)
West Ham (5) V Man UTD (9)
Resume: 5.30pm. Venue: London Stadium. On TV: Live on Sky Sports Main Event and Sky Sports Premier League.
West Ham will be without Michael Antonio – the striker has another hamstring problem, so record signing Sebastian Haller will get another chance. Winger Andrei Yarmolenko has returned to training after a self-inflicted injury but full-back Ryan Fredericks has a nervous problem.
Marcus Rashford is a skeptic because of the shoulder complaint. The United forward is being assessed after the Champions League defeat to Paris Saint-Germain. The match for Luke Shaw is coming very fast, but Axel Tuanzebe is available after being suspended in midweek.
Last season: Man UTD 1 West Ham 1, West Ham 2 Man UTD 0
Last five league matches: West Ham DLWWW; Man UTD DLWW
Top scorers (all matches): Sebastian Haller (West Ham) 6; Bruno Fernandes (Man UTD) 10
Inconsistencies: H 13-5 A 11-10 B 12-5
Referee: Andre Mariner (West Midlands)
Chelsea (3) v Leeds (12)
Resume: 8 p.m. Venue: Stamford Bridge. On TV: Live on Sky Sports Main Event and Sky Sports Premier League.
Blues boss Frank Lampard has a full-fledged fitness squad following Wednesday’s 4-0 Champions League match in Sevilla. Forward Olivier Giroud scored four goals in Spain for the first league start of the season.
Following on Everton’s victory, Leeds boss Marcelo Biels has been ruled out of action with a hamstring injury. Midfielders Pablo Hernandez (muscle difficulty) and Jamie Shackleton (thigh) continue to dispute their return to full fitness and are unlikely to be involved.
Last season: No related matches
Last five league matches: Chelsea DWWD; Leeds WLLDW
Top scorers (all matches): Timo Werner (Chelsea) 8; Patrick Bamford (Leeds) 7
Inconsistencies: H 8-15 A 5-1 D 10-3
Referee: Kevin Front (Leicestershire)
West Brom (18) v Crystal Palace (15)
Resume: 12pm. Venue: Hawthorne. On TV: Sky Sports Major Event and Sky Sports Football Live.
Albion defender Conor Townsend has been sidelined for six weeks after missing out on a win over Sheffield United with a knee injury. Bose Slaven Bilik will make a late decision on deputy Kieran Gibbs and midfielder Jake Livermore, who have returned to training after being tested positive for the corona virus.
The return of Wilfred Saha, who lost to Burnley and Newcastle after recording a positive Covid-19 Test, has given the palace momentum. Boss Roy Hodgson will replace Martin Kelly (calf) and Wayne Hennessy (thigh), Nathan Ferguson (knee) and Connor Wickham (thigh).
Last season: No related matches
Last five league matches: West Brom DLW; Crystal Palace WLWLL
Top scorers (all matches): Time Robinson & Hal Robson-Kanu (West Brom) 3; Wilfred Co. (Crystal Palace) 5
Inconsistencies: H 15-8 A 8-5 D 11-5
Referee: Paul Tearney (Lancashire)
Sheffield UTD (20) v Leicester (4)
Resume: 2.15 pm. Venue: Bramal Lane. On TV: Live on Sky Sports Main Event and Sky Sports Premier League.
The Blades will examine Enda Stevens and Ethan Ampot – Stevens has been treating a knee injury in recent weeks, with Ampadu missing out on the defeat issue in West Brom. Both defenders will be given until the last minute to prove their fitness.
Leicester’s Caglar Soyanku, Ricardo Pereira and Wes Morgan will be evaluated. Zoin has a nerve injury and is unlikely to be at risk after Pereira’s nerve is replaced, while Morgan has a back problem. Timothy Castagne (Hamstring) is still out but Daniel Amarti and Wilfred NDD are available.
Last season: Leicester 2 Chef UTD 0, Chef UTD 1 Leicester 2
Last five league matches: Chef UT LLL; Lester WWWLL
Top scorers (all matches): David McGoldrick (Chef UTD) 3; Jamie Verdy (Leicester) 10
Inconsistencies: H 14-5 A 1-1 D 5-2
Referee: Stuart Atwell (Warwickshire)
Tottenham (1) v Arsenal (14)
Resume: 4.30 pm. Venue: Tottenham Stadium. On TV: Sky Sports Major Event and Sky Sports Football Live.
Harry Kane missed Spurs’ 3-3 draw with Lask in the Europa League with an unexplained injury, but boss Jose Mourinho is expected to check out Stryker and feature him this weekend. Eric Lamela (Achilles) is out, evaluating Toby Alderware, Sergio Reguelon and Carlos Vinicius.
Arsenal wait for Thomas Party (thigh) and David Lewis in defeat against Wolf. Nicolas Pepe has been banned and Gabriel Martinelli (knee) is still out, with boss Michael Arteta preparing to recall all the great editors who retired for the Europa League on Thursday night.
Last season: Tottenham 2 Arsenal 1, Arsenal 2 Tottenham 2
Last five league matches: Tottenham WWWD; Arsenal LWLDL
Top scorers (all matches): Harry Kane (Tottenham) 13; Pierre-Emerick Obamayang & Nicolas Pepe (Arsenal) 4
Inconsistencies: H 19-20 A 3-1 D 5-2
Referee: Martin Atkinson (W Yorkshire)
Liverpool (2) V Wolves (7)
Resume: 7.15 pm. Venue: Anfield. On TV: Live on Premier Sports 1.
Liverpool goalkeeper Cavomin Keller has made his Premier League debut following the European bow representing Alison Becker (thigh) at midweek. Defender Trent Alexander-Arnold (calf) and Nabi Keita (hamstring) have returned to training so they can rejoin the team.
Wolf’s Raul Jimenez remains in hospital after suffering a fracture to his skull following a head-on collision with Arsenal’s victory over David Luiz, but is expected to be discharged early next week. After recovering from the corona virus, Roman Sayce is training again but Johnny is out with a knee injury.
Last season: Wolves 1 Liverpool 2, Liverpool 1 Wolves 0
Last five league matches: Liverpool WWDWD; Wolves DWLDW
Top scorers (all matches): Mohamed Salah (Liverpool) 10; Raoul Jimenez (Wolverhampton) 4
Inconsistencies: H 1-2 A 11-2 D 10-3
Referee: Craig Posen (South Yorkshire)
Brighton (16) v Southampton (6)
Resume: 8 p.m. Venue: Amex Stadium. On TV: Live on Sky Sports Main Event and Sky Sports Premier League.
Tariq Lampe is available for Brighton following the ban, but midfielder Adam Lallana faces a two-week interview following a nerve injury and fails against the former club. Striker Neil Ma uppei (hamstring) is a doubt, and Davy Proper and Alexis McAllister (sick) are returning to fitness.
Southampton striker Danny Ings will be evaluated ahead of the trip after training with the team for the first time following an injury to Aston Villa on November 1.
Last season: Southampton 1 Brighton 1, Brighton 0 Southampton 2
Last five league games: Brighton DLDWD; Southampton WWWDL
Top scorers (all matches): Neil Ma uppe (Brighton) 4; Danny Ings (Southampton) 5
Inconsistencies: H 6-4 A 15-8 D 23-10
Referee: David Coote (Nottinghamshire)