Joint pain, depression…a study lists all the neurological consequences of covid

Joint pain, depression...a study lists all the neurological consequences of covid

Since the beginning of the pandemic, scientists have been concerned about this Possible consequences Infection through it SARS-CoV-2 Patients may have long-term This possibility was soon confirmed as a reality, and many researchers have since focused on studying and understanding the nature, extent, and epidemiology of these consequences.

Large collective learning

Now, an article has been published in a scientific journal Nature Medicine has been evaluated Various neurological sequelae Disease is produced within one year after infection, and this was done in a large cohort: 154,068 covid 19 patients, 5,638,795 contemporary controls, and 5,859,621 historical controls. Data were obtained from the United States Department of Veterans Affairs Health Database.

With this approach, they determined that during the acute phase of Covid-19, the risk of neurological sequelae is higher. 1.42 and a rate of 70.69 per 1,000 personsEven in people who do not need hospitalization during the acute phase of the disease.

In particular, the researchers found that patients with Covid-19 saw increased the likelihood of their suffering Ischemic stroke, transient ischemic attack, hemorrhagic stroke, venous thrombosis, memory problems, Alzheimer’s, peripheral neuropathy, paresthesia, dysautonomia, Bell’s palsy, migraine, epilepsy, headache, cramps, seizure-like movement disease, dystonia, myoclonus, major depressive disorder in the year after infection disorder, stress/adjustment disorders, anxiety disorders, psychotic disorders, joint pain, myalgia, myopathy, hearing impairments or tinnitus, visual impairments, olfactory impairment, dysgeusia, dizziness, somnolence, somnolence, somnolence encephalitis or encephalopathy.

Joint pain and depression are the most common side effects

Between these, logically, the frequency varies. Thus, based on the additional load per 1,000 people, the consequences Very common They were joint pain, major depressive disorder, myalgia, stress/adjustment disorders, anxiety disorders, hearing disorders/tinnitus, memory problems, and dizziness.

The risk also varies with the age of the patients: although in general, any neurological disorder increases with age (especially in certain groups, episodic disorders, mental health disorders or musculoskeletal disorders) less frequent Elderly patient (cognitive, memory disorders or sensory disorders)

Although the hazard ratio and excess weight may seem small, the researchers caution that given the epidemiology of COVID-19, they are numbers that translate to many people in the real world. At the level of health policy, this affects the need to continue to take into account, Preventive measures Use of masks or vaccination, as well as implementing long-term strategies to care for all potentially infected people.


Xu, E., Xie, Y. & Al-Aly, Z. Long-term neurological outcomes of COVID-19. Nat Med (2022). DOI:

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